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1

A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates

Hannu Mönkkönen, Seppo Auriola, Petri Lehenkari, Maarit Kellinsalmi, Ilmo E Hassinen, Jouko Vepsäläinen, Jukka Mönkkönen

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 282 KB

english, 2006

2

Analysis of unstirred water layer in in vitro permeability experiments

Timo Korjamo, Aki T. Heikkinen, Jukka Mönkkönen

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 205 KB

english, 2009

3

Quantitative determination of cholesterol, sitosterol, and sitostanol in cultured Caco-2 cells by liquid chromatography–atmospheric pressure chemical ionization mass spectrometry

Joni J. Palmgrén, Anu Töyräs, Timo Mauriala, Jukka Mönkkönen, Seppo Auriola

Journal:

Journal of Chromatography B

Year:

2005

Language:

english

File:

PDF, 361 KB

english, 2005

4

Opsonization, Biodistribution, Cellular Uptake and Apoptosis Study of PEGylated PBCA Nanoparticle as Potential Drug Delivery Carrier

Kiran Ramanlal Chaudhari, Mukesh Ukawala, Arehalli S. Manjappa, Abhinesh Kumar, Piyush Kishor Mundada, Anil Kumar Mishra, Rashi Mathur, Jukka Mönkkönen, Rayasa S. Ramchandra Murthy

Journal:

Pharmaceutical Research

Year:

2012

Language:

english

File:

PDF, 913 KB

english, 2012

5

Energy availability, abundance, energy-use and species richness in forest bird communities: a test of the species–energy theory

Mikko Mönkkönen, Jukka T. Forsman, Folmer Bokma

Journal:

Global Ecology and Biogeography

Year:

2006

Language:

english

File:

PDF, 356 KB

english, 2006

6

Measurement of hydration in the stratum corneum with the MoistureMeter and comparison with the Corneometer

Esko Alanen, Jouni Nuutinen, Kirsi Nicklén, Tapani Lahtinen, Jukka Mönkkönen

Journal:

Skin Research and Technology

Year:

2004

Language:

english

File:

PDF, 227 KB

english, 2004

7

Targeting Efficiency and Biodistribution of Zoledronate Conjugated Docetaxel Loaded Pegylated PBCA Nanoparticles for Bone Metastasis

Kiran R. Chaudhari, Abhinesh Kumar, Vinoth Kumar Megraj Khandelwal, Anil K. Mishra, Jukka Monkkonen, Rayasa S. Ramachandra Murthy

Journal:

Advanced Functional Materials

Year:

2012

Language:

english

File:

PDF, 3.73 MB

english, 2012

8

Bone metastasis targeting: A novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel

Kiran Ramanlal Chaudhari, Abhinesh Kumar, Vinoth Kumar Megraj Khandelwal, Mukesh Ukawala, Arehalli S. Manjappa, Anil Kumar Mishra, Jukka Monkkonen, Rayasa S. Ramachandra Murthy

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

9

EFFECTS OF PREDATION ON COMMUNITY ASSEMBLY AND SPATIAL DISPERSION OF BREEDING FOREST BIRDS

Forsman, Jukka T., Mönkkönen, Mikko, Hukkanen, Markku

Journal:

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

10

Effects of low-dose, noncytotoxic, intraarticular liposomal clodronate on development of erosions and proteoglycan loss in established antigen-induced arthritis in rabbits

Arnoldas C̆eponis, Eero Waris, Jukka Mönkkönen, Leena Laasonen, Mika Hyttinen, Svetlana A. Solovieva, Roeland Hanemaaijer, Andreas Bitsch, Yrjö T. Konttinen

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 1.84 MB

english, 2001

11

The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: Evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis

Julie C. Frith, Jukka Mönkkönen, Seppo Auriola, Hannu Mönkkönen, Michael J. Rogers

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 1.05 MB

english, 2001

12

Macrophage-like RAW 264 cell line and time-resolved fluoroimmunoassay (TRFIA) as tools in screening drug effects on cytokine secretion

Niina Pennanen, Seppo Lapinjoki, Anne Palander, Arto Urtti, Jukka Mönkkönen

Journal:

International Journal of Immunopharmacology

Year:

1995

Language:

english

File:

PDF, 544 KB

english, 1995

13

Protein concentration and pH affect the apparent P-glycoprotein–ATPase activation kinetics

Aki T. Heikkinen, Jukka Mönkkönen

Journal:

International Journal of Pharmaceutics

Year:

2008

Language:

english

File:

PDF, 122 KB

english, 2008

14

Transferrin mediated solid lipid nanoparticles containing curcumin: Enhanced in vitro anticancer activity by induction of apoptosis

Rohit S. Mulik, Jukka Mönkkönen, Risto O. Juvonen, Kakasaheb R. Mahadik, Anant R. Paradkar

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 1005 KB

english, 2010

15

Comparison of in vitro cell models in predicting in vivo brain entry of drugs

Jenni J. Hakkarainen, Aaro J. Jalkanen, Tiina M. Kääriäinen, Pekka Keski-Rahkonen, Tetta Venäläinen, Juho Hokkanen, Jukka Mönkkönen, Marjukka Suhonen, Markus M. Forsberg

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 765 KB

english, 2010

16

Analysis of (dichloromethylene) bisphosphonate in urine by capillary gas chromatography—mass spectrometry

Seppo Auriola, Risto Kostiainen, Markku Ylinen, Jukka Mönkkönen, Pauli Ylitalo

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

1989

Language:

english

File:

PDF, 467 KB

english, 1989

17

Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography–electrospray ionization mass spectrometry

Marjo Jauhiainen, Hannu Mönkkönen, Johanna Räikkönen, Jukka Mönkkönen, Seppo Auriola

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 658 KB

english, 2009

18

Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography–electrospray mass spectrometry

Seppo Auriola, Julie Frith, Michael J Rogers, Antti Koivuniemi, Jukka Mönkkönen

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 210 KB

english, 1997

19

Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography–electrospray ionisation mass spectrometry

Hannu Mönkkönen, Päivi Moilanen, Jukka Mönkkönen, Julie C Frith, Michael J Rogers, Seppo Auriola

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

2000

Language:

english

File:

PDF, 436 KB

english, 2000

20

Effects of various absorption enhancers on transport of clodronate through Caco-2 cells

Johanna Raiman, Soili Törmälehto, Kirsi Yritys, Hans E Junginger, Jukka Mönkkönen

Journal:

International Journal of Pharmaceutics

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

21

Physicochemical and morphological properties of complexes made of cationic liposomes and oligonucleotides

Ilpo Jääskeläinen, Brigitte Sternberg, Jukka Mönkkönen, Arto Urtti

Journal:

International Journal of Pharmaceutics

Year:

1998

Language:

english

File:

PDF, 1.92 MB

english, 1998

22

Enhancement of percutaneous absorption of naproxen by phospholipids

Riitta Valjakka-Koskela, Merja Kirjavainen, Jukka Mönkkönen, Arto Urtti, Juha Kiesvaara

Journal:

International Journal of Pharmaceutics

Year:

1998

Language:

english

File:

PDF, 530 KB

english, 1998

23

The role of climate in limiting European resident bird populations

Jukka T. Forsman, Mikko Mönkkönen

Journal:

Journal of Biogeography

Year:

2003

Language:

english

File:

PDF, 203 KB

english, 2003

24

Aminobisphosphonate-pretreated dendritic cells trigger successful Vγ9Vδ2 T cell amplification for immunotherapy in advanced cancer patients

Florian Cabillic, Olivier Toutirais, Vincent Lavoué, Cécile Thomas de La Pintière, Pascale Daniel, Nathalie Rioux-Leclerc, Bruno Turlin, Hannu Mönkkönen, Jukka Mönkkönen, Karim Boudjema, Véronique Cat

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 452 KB

english, 2010

25

Positive interactions between migrant and resident birds: testing the heterospecific attraction hypothesis

Robert L. Thomson, Jukka T. Forsman, Mikko Mönkkönen

Journal:

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

26

Heterospecific attraction and food resources in migrants' breeding patch selection in northern boreal forest

Jukka T. Forsman, Mikko Mönkkönen, Pekka Helle, Jouko Inkeröinen

Journal:

Year:

1998

Language:

english

File:

PDF, 234 KB

english, 1998

27

Effect of locally administered zoledronic acid on injury-induced intramembranous bone regeneration and osseointegration of a titanium implant in rats

Simo S. A. Miettinen, Jarkko Jaatinen, Alpo Pelttari, Reijo Lappalainen, Jukka Mönkkönen, Petri K. Venesmaa, Heikki P. J. Kröger

Journal:

Journal of Orthopaedic Science

Year:

2009

Language:

english

File:

PDF, 246 KB

english, 2009

28

Metabolic and Efflux Properties of Caco-2 Cells Stably Transfected with Nuclear Receptors

Timo Korjamo, Jukka Mönkkönen, Jouko Uusitalo, Miia Turpeinen, Olavi Pelkonen, Paavo Honkakoski

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 439 KB

english, 2006

29

The Asymmetry of the Unstirred Water Layer in Permeability Experiments

Timo Korjamo, Aki T. Heikkinen, Pekka Waltari, Jukka Mönkkönen

Journal:

Pharmaceutical Research

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

30

Erratum to: Opsonization, Biodistribution, Cellular Uptake and Apoptosis Study of PEGylated PBCA Nanoparticle as Potential Drug Delivery Carrier

Kiran Ramanlal Chaudhari, Mukesh Ukawala, Arehalli S. Manjappa, Abhinesh Kumar, Piyush Kishor Mundada, Anil Kumar Mishra, Rashi Mathur, Jukka Mönkkönen, Rayasa S. Ramchandra Murthy

Journal:

Pharmaceutical Research

Year:

2011

Language:

english

File:

PDF, 55 KB

english, 2011

31

Effects of calcium and lipophilicity on transport of clodronate and its esters through Caco-2 cells

Johanna Raiman, Riku Niemi, Jouko Vepsäläinen, Kirsi Yritys, Tomi Järvinen, Jukka Mönkkönen

Journal:

International Journal of Pharmaceutics

Year:

2001

Language:

english

File:

PDF, 132 KB

english, 2001

32

Qualitative geographical variation in interspecific interactions

Mikko Mönkkönen, Jukka T. Forsman, Robert L. Thomson

Journal:

Year:

2004

Language:

english

File:

PDF, 146 KB

english, 2004

33

Fear factor: prey habitat selection and its consequences in a predation risk landscape

Robert L. Thomson, Jukka T. Forsman, Francesc Sardà-Palomera, Mikko Mönkkönen

Journal:

Year:

2006

Language:

english

File:

PDF, 139 KB

english, 2006

34

Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro

Johanna Räikkönen, Julie C Crockett, Michael J Rogers, Hannu Mönkkönen, Seppo Auriola, Jukka Mönkkönen

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 391 KB

english, 2009

35

Landscape characteristics associated with the occurrence of the flying squirrel Pteromys volans in old-growth forests of northern Finland

Mikko Mönkkönen, Pasi Reunanen, Ari Nikula, Jouko Inkeröinen, Jukka Forsman

Journal:

Year:

1997

Language:

english

File:

PDF, 692 KB

english, 1997

36

Genetic diversity in the Siberian jay Perisoreus infaustus in fragmented old-growth forests of Fennoscandia

Leena Uimaniemi, Markku Orell, Mikko Mönkkönen, Esa Huhta, Jukka Jokimäki, Jaakko Lumme

Journal:

Year:

2000

Language:

english

File:

PDF, 265 KB

english, 2000

37

In vitro Comparison of Clodronate, Pamidronate and Zoledronic Acid Effects on Rat Osteoclasts and Human Stem Cell-Derived Osteoblasts

Maarit Kellinsalmi, Hannu Mönkkönen, Jukka Mönkkönen, Hannu-Ville Leskelä, Vilhelmiina Parikka, Martti Hämäläinen, Petri Lehenkari

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 351 KB

english, 2005

38

Modelling of Drug Disposition Kinetics in In Vitro Intestinal Absorption Cell Models

Aki T. Heikkinen, Timo Korjamo, Jukka Mönkkönen

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 427 KB

english, 2010

39

In vitro and in vivo effects of tetrakisphosphonates on bone resorption, tumor osteolysis, ectopic calcification, and macrophages

Joel M. Van Gelder, Eli Breuer, Ada Schlossman, Asher Ornoy, Jukka Mönkkönen, Johanna Similä, Thomas Klenner, Heidi Stadler, Burkhard Krempien, N. Patlas, Gershon Golomb

Journal:

Journal of Pharmaceutical Sciences

Year:

1997

Language:

english

File:

PDF, 224 KB

english, 1997

40

Clodronate and Liposome-Encapsulated Clodronate Are Metabolized to a Toxic ATP Analog, Adenosine 5′-(β,γ-Dichloromethylene) Triphosphate, by Mammalian Cells In Vitro

Julie C. Frith, Jukka Mönkkönen, G. Michael Blackburn, R. Graham G. Russell, Michael J. Rogers

Journal:

Journal of Bone and Mineral Research

Year:

1997

Language:

english

File:

PDF, 422 KB

english, 1997

41

Evolution of heterospecific attraction: using other species as cues in habitat selection

Mikko Mönkkönen, Roger Härdling, Jukka T. Forsman, Juha Tuomi

Journal:

Evolutionary Ecology

Year:

1999

Language:

english

File:

PDF, 168 KB

english, 1999

42

Inhibition of Growth of Dictyostelium discoideum Amoebae by Bisphosphonate Drugs Is Dependent on Cellular Uptake

Michael J. Rogers, Xiaojuan Xiong, Xiaohui Ji, Jukka Mönkkönen, R. Graham G. Russell, Michael P. Williamson, Frank H. Ebetino, Donald J. Watts

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 555 KB

1997

43

The Cellular Uptake and Metabolism of Clodronate in RAW 264 Macrophages

Hannu Mönkkönen, Michael J. Rogers, Niina Makkonen, Sanna Niva, Seppo Auriola, Jukka Mönkkönen

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 165 KB

english, 2001

44

Effect of Liposomal and Free Bisphosphonates on the IL-1β, IL-6 and TNFα Secretion from RAW 264 Cells in Vitro

Niina Pennanen, Seppo Lapinjoki, Arto Urtti, Jukka Mönkkönen

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.06 MB

1995

45

Synthesis and Preclinical Pharmacology of 2-(2-Aminopyrimidinio) Ethylidene-1,1-Bisphosphonic Acid Betaine (ISA-13-1)-A Novel Bisphosphonate

Hagit Cohen, Ivan S. Alferiev, Jukka Mönkkönen, Markus J. Seibel, Taly Pinto, Aviva Ezra, Vered Solomon, David Stepensky, Hilah Sagi, Asher Ornoy, Natan Patlas, Gerhard Hägele, Amnon Hoffman, Eli Breu

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.64 MB

1999

46

Liposome-Mediated Delivery of Gallium to Macrophage-Like Cellsin Vitro: Demonstration of a Transferrin-Independent Route for Intracellular Delivery of Metal Ions

Jukka Mönkkönen, Carolyn S. Brown, Tormaine T. Thompson, Timothy D. Heath

Journal:

Pharmaceutical Research

Year:

1993

File:

PDF, 1.04 MB

1993

47

Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

Anke J. Roelofs, Marjo Jauhiainen, Hannu Mönkkönen, Michael J. Rogers, Jukka Mönkkönen, Keith Thompson

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 215 KB

english, 2009

48

Responses by breeding birds to heterospecific song and mobbing call playbacks under varying predation risk

Jukka T. Forsman, Mikko Mönkkönen

Journal:

Animal Behaviour

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

49

Studies on liposome formulations for intra-articular delivery of clodronate

Jukka Mönkkönen, Jaana Liukkonen, Markku Taskinen, Timothy D. Heath, Arto Urtti

Journal:

Journal of Controlled Release

Year:

1995

Language:

english

File:

PDF, 720 KB

english, 1995

50

The effects of liposome surface charge and size on the intracellular delivery of clodronate and gallium in vitro

Jukka Mönkkönen, Riitta Valjakka, Maria Hakasalo, Arto Urtti

Journal:

International Journal of Pharmaceutics

Year:

1994

Language:

english

File:

PDF, 667 KB

english, 1994